Gpr6 - SNV Details



 Gene Information 
Gene Name Gpr6
Old Gene Names for Gpr6 Ai852874 , Gm233
Gene Description G protein-coupled receptor 6 [Source:MGI Symbol;Acc:MGI:2155249]
MGI phenotype Homozygous mutation of this gene does not appear to result in a phenotype.
Uniprot Name
CCDS Name
Gene GO
positive regulation of cytosolic calcium ion concentration; integral component of membrane; sphingosine-1-phosphate receptor activity; G-protein coupled receptor activity; G-protein coupled receptor signaling pathway; plasma membrane; sphingosine-1-phosphate signaling pathway
Homolog in other species GPR6
Omim http://omim.org/entry/600553
Immgen Expression
MEDIAN(LOWER IN DC8+.TH, TGD.VG5+.ACT.IEL)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000046922
Chromosome 10
Coordinate 41,070,816     (Assembly: GRCm38)    
Ref Base C
Var Base T
Zygosity Heterozygous
Read Depth 31
Allele Frequency
C:R0.45
T:V0.55
Amino Acid Change A->T (Alanine -> Threonine)
Sample ID IGL00309
Median Base Quality 33
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 27 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability