Kidins220 - SNV Details

 Gene Information 
Gene Name Kidins220
Gene Description kinase D-interacting substrate 220 [Source:MGI Symbol;Acc:MGI:1924730]
MGI phenotype Mice homozygous for a knock-out allele exhibit embryonic lethality. Mice heterozygous for a knock-out allele exhibit decreased dendritic complexity in the barrel somatosensory cortex and dentate gyrus neurons.
Uniprot Name
Gene GO
dendrite morphogenesis; protein binding; in utero embryonic development
Homolog in other species KIDINS220
Immgen Expression
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000036333
Chromosome 12
Coordinate 25,057,474     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 44
Allele Frequency
Amino Acid Change D->G (Aspartic acid -> Glycine)
Sample ID IGL00978
Median Base Quality 38
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 36 Other Mutations

Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved