Tas2r139 - SNV Details



 Gene Information 
Gene Name Tas2r139
Gene Description taste receptor, type 2, member 139 [Source:MGI Symbol;Acc:MGI:2681308]
Uniprot Name
CCDS Name
Gene GO
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
detection of chemical stimulus involved in sensory perception of bitter taste
integral to membrane
membrane
receptor activity
response to stimulus
sensory perception of taste
taste receptor activity
Homolog in other species TAS2R39
Immgen Expression
LOW
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000047102
Chromosome 6
Coordinate 42,141,121     (Assembly: GRCm38)    
Ref Base T
Codon Change agT/agG
Var Base G
Zygosity Heterozygous
Read Depth 39
Allele Frequency
T:0.46
G:0.54
Amino Acid Position 62
Amino Acid Change S->R (Serine -> Arginine)
Sample ID IGL00863
Median Base Quality 38
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 28 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000062919:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Mammalian taste receptor TAS2_rcpt IPR007960 ENSMUSP00000062919 Pfam 17
306 Description available Search pathways
GPCR, rhodopsin-like, 7TM GPCR_Rhodpsn_7TM IPR017452 ENSMUSP00000062919 Prosite_profiles 35
255 Description available Search pathways

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved