Inpp4b - SNV Details



 Gene Information 
Gene Name Inpp4b
Old Gene Names for Inpp4b E130107i17rik
Gene Description inositol polyphosphate-4-phosphatase, type II [Source:MGI Symbol;Acc:MGI:2158925]
Uniprot Name
CCDS Name
Gene GO
4-bisphosphate 4-phosphatase activity
5-bisphosphate 4-phosphatase activity
cellular_component
hydrolase activity
phosphatidylinositol-3
phosphatidylinositol-4
protein binding
Homolog in other species INPP4B
Immgen Expression
LOW(HIGH IN TGD GROUP, ABT GROUP, TACTIVATION GROUP)
Gnf Expression
MEDIAN(HIGH IN IMM.G1, IMM.G3)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000037940
Chromosome 8
Coordinate 81,856,750     (Assembly: GRCm38)    
Ref Base A
Codon Change cAg/cGg
Var Base G
Zygosity Heterozygous
Read Depth 22
Allele Frequency
A:0.45
G:0.55
Amino Acid Position 144
Amino Acid Change Q->R (Glutamine -> Arginine)
Sample ID IGL00850
Median Base Quality 38
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 30 Other Mutations

 Predictions 
Polyphen Score 0.99
Polyphen Prediction Probably damaging
Sift Score 0.12
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000044466:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
C2_Ca/lipid-bd_dom_CaLB IPR008973 ENSMUSP00000044466 Superfamily 43
181

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved