Lmtk2 - SNV Details



 Gene Information 
Gene Name Lmtk2
Old Gene Names for Lmtk2 2900041g10rik , A330101p12rik
Gene Description lemur tyrosine kinase 2 [Source:MGI Symbol;Acc:MGI:3036247]
Uniprot Name
CCDS Name
Gene GO
transferring phosphorus-containing groups
ATP binding
Golgi apparatus
early endosome
early endosome to late endosome transport
endocytic recycling
integral to membrane
myosin VI binding
nucleotide binding
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
Homolog in other species LMTK2
Omim http://omim.org/entry/610989
Immgen Expression
MEDIAN(HIGHER IN MYELOID GROUP, TGD.VG5+.ACT.IEL)
Gnf Expression
MEDIAN/HIGH(LOWER IN PANCREAS, KIDNEY, LIVER, BROWNFAT, SPLEEN, IMM.G2, THYROID, GI GROUP)
MEDIAN(HIGH IN OLFACTORYBULB)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000038970
Chromosome 5
Coordinate 144,176,398     (Assembly: GRCm38)    
Ref Base A
Codon Change gAg/gGg
Var Base G
Zygosity Heterozygous
Read Depth 13
Allele Frequency
A:0.46
G:0.54
Amino Acid Position 1312
Amino Acid Change E->G (Glutamic acid -> Glycine)
Sample ID IGL00848
Median Base Quality 37
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 53 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.19
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved