Fcamr - SNV Details



 Gene Information 
Gene Name Fcamr
Gene Description Fc receptor, IgA, IgM, high affinity [Source:MGI Symbol;Acc:MGI:1927803]
MGI phenotype Homozygous null mice have enhanced germinal center formation, affinity maturation and memory induction of IgG3 producing B cells after immunization with T cell-independent antigens.
Uniprot Name
CCDS Name
Gene GO
IgA binding
IgM binding
immune response
integral to membrane
plasma membrane
transmembrane receptor activity
Homolog in other species FCAMR
Omim http://omim.org/entry/605484
Immgen Expression
MEDIAN
Gnf Expression
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000026415
Chromosome 1
Coordinate 130,813,214     (Assembly: GRCm38)    
Ref Base G
Codon Change Gtg/Atg
Var Base A
Zygosity Heterozygous
Read Depth 13
Allele Frequency
G:0.54
A:0.46
Amino Acid Position 457
Amino Acid Change V->M (Valine -> Methionine)
Sample ID IGL00840
Median Base Quality 35
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 34 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.21
Sift Prediction tolerated

 Availability Details 
Availability Progeny Cryopreserved