Camk2g - SNV Details



 Gene Information 
Gene Name Camk2g
Old Gene Names for Camk2g 5930429p18rik , Camkg
Gene Description calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259]
MGI phenotype Mice homozygous for a knock-out allele exhibit female infertility and decreased sensitivity of macrophages to ER stress-induced apoptosis.
Uniprot Name
CCDS Name
Gene GO
transferring phosphorus-containing groups
ATP binding
G1/S transition of mitotic cell cycle
calcium ion transport
calmodulin binding
calmodulin-dependent protein kinase activity
nucleotide binding
protein autophosphorylation
protein kinase activity
protein phosphorylation
protein serine/threonine kinase activity
Homolog in other species CAMK2G
Omim http://omim.org/entry/602123
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
HIGH(HIGHER IN IMM GROUP, NS GROUPS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000021820
Chromosome 14
Coordinate 20,737,330     (Assembly: GRCm38)    
Ref Base C
Codon Change Ggc/Agc
Var Base T
Zygosity Heterozygous
Read Depth 12
Allele Frequency
C:0.33
T:0.67
Amino Acid Position 477
Amino Acid Change G->S (Glycine -> Serine)
Sample ID IGL00822
Median Base Quality 35
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 28 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.26
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Protein domains 
ENSMUSP00000098398:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Calcium/calmodulin-dependent protein kinase II, association-domain Ca/CaM-dep_prot_kinase-assoc IPR013543 ENSMUSP00000098398 Pfam 363
490 Description available Search pathways

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved