Wwp1 - SNV Details



 Gene Information 
Gene Name Wwp1
Old Gene Names for Wwp1 8030445b08rik
Gene Description WW domain containing E3 ubiquitin protein ligase 1 [Source:MGI Symbol;Acc:MGI:1861728]
Uniprot Name
CCDS Name
Gene GO
ubiquitin-protein transferase activity; proteasome-mediated ubiquitin-dependent protein catabolic process; negative regulation of transcription
DNA-templated; cytoplasm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein binding; protein ubiquitination; nucleus; lung development; plasma membrane; ligase activity; T cell differentiation
Homolog in other species WWP1
Omim http://omim.org/entry/602307
Immgen Expression
MEDIAN(HIGH IN TGD.VG5+.ACT.IEL, NK GROUP, T.8EFF.SP.OT1.D6.VSVOVA, DC.LC.SK, MYELOID GROUP)
Gnf Expression
MEDIAN(HIGH IN MACROPHAGES, OSTEOCLASTS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000041058
Chromosome 4
Coordinate 19,650,360     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 41
Allele Frequency
T:R0.51
C:V0.49
Amino Acid Change T->A (Threonine -> Alanine)
Sample ID IGL00156
Median Base Quality 39
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 28 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign

 Availability Details 
Availability Cryopreserved