Itgad - SNV Details



 Gene Information 
Gene Name Itgad
Gene Description integrin, alpha D [Source:MGI Symbol;Acc:MGI:3578624]
Uniprot Name
CCDS Name
Gene GO
cell adhesion; metal ion binding; activated T cell proliferation; integral component of membrane; integrin complex; integrin-mediated signaling pathway
Homolog in other species ITGAD
Omim http://omim.org/entry/602453
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
LOW/MEDIAN(HIGH IN MF.RP.SP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000070369
Chromosome 7
Coordinate 128,193,716     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 40
Allele Frequency
A:R0.57
G:V0.42
Amino Acid Change Y->C (Tyrosine -> Cysteine)
Sample ID IGL02735
Median Base Quality 37
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 50 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved