Mcpt4 - SNV Details



 Gene Information 
Gene Name Mcpt4
Old Gene Names for Mcpt4 Mcp-4
Gene Description mast cell protease 4 [Source:MGI Symbol;Acc:MGI:96940]
MGI phenotype Homozygous inactivation of this locus affects thrombin regulation and fibronectin turnover.
Uniprot Name
CCDS Name
Gene GO
catalytic activity; intracellular; peptidase activity; regulation of angiotensin levels in blood; proteolysis; secretory granule; serine-type endopeptidase activity
Immgen Expression
LOW
Gnf Expression
HIGH
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000061068
Chromosome 14
Coordinate 56,060,667     (Assembly: GRCm38)    
Ref Base C
Var Base T
Zygosity Heterozygous
Read Depth 14
Allele Frequency
C:R0.50
T:V0.50
Amino Acid Change M->I (Methionine -> Isoleucine)
Sample ID IGL02733
Median Base Quality 39.5
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 35 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign

 Availability Details 
Availability Cryopreserved