Wdtc1 - SNV Details



 Gene Information 
Gene Name Wdtc1
Gene Description WD and tetratricopeptide repeats 1 [Source:MGI Symbol;Acc:MGI:2685541]
Uniprot Name
CCDS Name
Gene GO
enzyme inhibitor activity; negative regulation of fatty acid biosynthetic process; protein binding; protein ubiquitination; nucleus; glucose metabolic process; in utero embryonic development; cytosol; multicellular organism growth; histone deacetylase binding; negative regulation of transcription from RNA polymerase II promoter; regulation of cell size; histone binding; negative regulation of catalytic activity; cellular chemical homeostasis; cellular response to insulin stimulus
Homolog in other species WDTC1
Immgen Expression
MEDIAN(HIGHER IN PROB.FRBC.FL, PREB.FRD.FL, T.DPSM.TH, TGD.TH)
Gnf Expression
MEDIAN(HIGHER IN TESTIS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000037622
Chromosome 4
Coordinate 133,297,478     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 46
Allele Frequency
A:R0.37
T:V0.63
Amino Acid Change S->R (Serine -> Arginine)
Sample ID IGL02724
Median Base Quality 38
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 67 Other Mutations

 Predictions 
Polyphen Score 0.22
Polyphen Prediction Benign

 Availability Details 
Availability Cryopreserved