Capn2 - SNV Details



 Gene Information 
Gene Name Capn2
Old Gene Names for Capn2 Ai326419 , Capa2
Gene Description calpain 2 [Source:MGI Symbol;Acc:MGI:88264]
Uniprot Name
CCDS Name
Gene GO
pseudopodium; protein autoprocessing; cytoplasm; endoplasmic reticulum; intracellular; membrane raft; blastocyst development; response to hypoxia; protein binding; peptidase activity; nucleus; calcium-dependent cysteine-type endopeptidase activity; cytosol; extracellular vesicular exosome; myoblast fusion; cellular response to amino acid stimulus; chromatin; perinuclear endoplasmic reticulum; proteolysis; plasma membrane; dendrite; calcium ion binding; cytoskeletal protein binding; Golgi apparatus; protein heterodimerization activity
Homolog in other species CAPN2
Omim http://omim.org/entry/114230
Immgen Expression
MEDIAN(HIGH IN TGD GROUP, NK GROUP, T.8EFF.SP.OT1.D6.VSVOVA, T.4MEM.SP)
Gnf Expression
HIGH(LOWER IN FERTILIZEDEGG, PANCREAS, BROWNFAT, THYROID)
MEDIAN(HIGH IN M1)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000026509
Chromosome 1
Coordinate 182,472,584     (Assembly: GRCm38)    
Ref Base T
Var Base A
Zygosity Heterozygous
Read Depth 32
Allele Frequency
T:R0.59
A:V0.41
Amino Acid Change I->F (Isoleucine -> Phenylalanine)
Sample ID IGL02679
Median Base Quality 39
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 48 Other Mutations

 Predictions 
Polyphen Score 0.11
Polyphen Prediction Benign
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved