Gng7 - SNV Details



 Gene Information 
Gene Name Gng7
Old Gene Names for Gng7 Ai840417
Gene Description guanine nucleotide binding protein (G protein), gamma 7 [Source:MGI Symbol;Acc:MGI:95787]
MGI phenotype Mice homozygous for a knock-out allele exhibit an enhanced startle response, loss of dopamine- and forskolin-stimulated adenylyl cyclase activity in the striatum, and increased mean insulin levels in males.
Uniprot Name
CCDS Name
Gene GO
behavioral fear response; heterotrimeric G-protein complex; regulation of adenylate cyclase activity; extracellular vesicular exosome; G-protein coupled receptor signaling pathway; signal transducer activity; locomotory behavior; receptor guanylyl cyclase signaling pathway
Homolog in other species GNG7
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Gnf Expression
MEDIAN(HIGH IN CEREBELLUM, OLFACTORYBULB, DORSALROOTGANGLION, HIPPOCAMPUS, AMYGDALA, FRONTALCORTEX, CEREBRALCORTEX, CORTEX, PREOPTIC, SUBSTANTIANIGRA, HYPOTHALAMUS)
MEDIAN(HIGH IN CEREBELLUM, OLFACTORYBULB, DORSALROOTGANGLION, HIPPOCAMPUS, AMYGDALA, FRONTALCORTEX, CEREBRALCORTEX, CORTEX, PREOPTIC, SUBSTANTIANIGRA, HYPOTHALAMUS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000048240
Chromosome 10
Coordinate 80,951,684     (Assembly: GRCm38)    
Ref Base C
Var Base A
Zygosity Heterozygous
Read Depth 25
Allele Frequency
C:R0.52
A:V0.48
Amino Acid Change L->F (Leucine -> Phenylalanine)
Sample ID IGL02678
Median Base Quality 40
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 58 Other Mutations

 Predictions 

 Availability Details 
Availability Cryopreserved