Sstr4 - SNV Details



 Gene Information 
Gene Name Sstr4
Old Gene Names for Sstr4 Smstr4
Gene Description somatostatin receptor 4 [Source:MGI Symbol;Acc:MGI:105372]
MGI phenotype Homozygote null mice have increased susceptibility to inflammation, delayed type hypersensitivity, hyperalgesia and airway hypersensitivity.
Uniprot Name
CCDS Name
Gene GO
somatostatin receptor activity; cytoplasm; negative regulation of cAMP metabolic process; arachidonic acid metabolic process; positive regulation of MAPK cascade; protein binding; integral component of membrane; cell migration; G-protein coupled receptor activity; G-protein coupled receptor signaling pathway; cellular response to glucocorticoid stimulus; somatostatin signaling pathway; forebrain development; plasma membrane
Homolog in other species SSTR4
Omim http://omim.org/entry/182454
Immgen Expression
MEDIAN
Gnf Expression
MEDIAN(HIGH IN CEREBELLUM, OLFACTORYBULB, DORSALROOTGANGLION, HIPPOCAMPUS, AMYGDALA, FRONTALCORTEX, CEREBRALCORTEX, CORTEX, PREOPTIC, SUBSTANTIANIGRA, HYPOTHALAMUS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000037014
Chromosome 2
Coordinate 148,396,533     (Assembly: GRCm38)    
Ref Base G
Var Base T
Zygosity Heterozygous
Read Depth 44
Allele Frequency
G:R0.50
T:V0.50
Amino Acid Change G->Stop (Glycine -> Stop)
Sample ID IGL02670
Median Base Quality 38
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 28 Other Mutations

 Predictions 
Polyphen Prediction N/A
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved