Dock10 - SNV Details



 Gene Information 
Gene Name Dock10
Old Gene Names for Dock10 A630054m16rik , R75174 , 9330153b10rik
Gene Description dedicator of cytokinesis 10 [Source:MGI Symbol;Acc:MGI:2146320]
Uniprot Name
CCDS Name
Gene GO
Rho guanyl-nucleotide exchange factor activity; protein binding; binding; cellular_component; GTP binding; Rho GTPase binding; phospholipid binding
Homolog in other species DOCK10
Omim http://omim.org/entry/611518
Immgen Expression
MEDIAN(HIGH IN BCELL GROUP, DC.PDC.8-.SP, DC.PDC.8+.SP)
Gnf Expression
LOW/MEDIAN(HIGH IN IMM GROUP, OSTEO GROUP, SPLEEN, TRACHEA, LUNG, ADIPOSETISSUE)
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000038608
Chromosome 1
Coordinate 80,574,123     (Assembly: GRCm38)    
Ref Base T
Var Base A
Zygosity Heterozygous
Read Depth 21
Allele Frequency
T:R0.48
A:V0.52
Amino Acid Change Y->F (Tyrosine -> Phenylalanine)
Sample ID IGL02649
Median Base Quality 38
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 48 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Cryopreserved