Polr3c - SNV Details



 Gene Information 
Gene Name Polr3c
Old Gene Names for Polr3c 4933407e01rik
Gene Description polymerase (RNA) III (DNA directed) polypeptide C [Source:MGI Symbol;Acc:MGI:1921664]
Uniprot Name
CCDS Name
Gene GO
transcription
DNA-dependent; DNA binding; nucleus; positive regulation of interferon-beta production; innate immune response; defense response to virus; DNA-directed RNA polymerase activity; positive regulation of innate immune response; molecular_function
Homolog in other species POLR3C
Immgen Expression
HIGH
Gnf Expression
HIGH(HIGHER IN IMM.G1, IMM.G3, AND EMB GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000028099
Chromosome 3
Coordinate 96,716,686     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 25
Allele Frequency
G:R0.52
A:V0.48
Amino Acid Change T->M (Threonine -> Methionine)
Sample ID IGL02640
Median Base Quality 39
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 35 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved