Trmt5 - SNV Details



 Gene Information 
Gene Name Trmt5
Old Gene Names for Trmt5 2610027o18rik
Gene Description TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1923607]
Uniprot Name
CCDS Name
Gene GO
RNA methylation; 7-methylguanosine RNA capping; tRNA (guanine(37)-N(1))-methyltransferase activity; transferase activity; nucleus; cellular_component; methyltransferase activity; mitochondrial matrix; biological_process; molecular_function
Homolog in other species TRMT5
Omim http://omim.org/entry/611023
Immgen Expression
MEDIAN(LOWER IN MYELOID GROUP, DC.LC.SK)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000034442
Chromosome 12
Coordinate 73,281,455     (Assembly: GRCm38)    
Ref Base A
Codon Change Tcc/Acc
Var Base T
Zygosity Heterozygous
Read Depth 51
Allele Frequency
A:R0.47
T:V0.53
Amino Acid Position 325
Amino Acid Change S->T (Serine -> Threonine)
Sample ID IGL02627
Median Base Quality 39
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 29 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000112121:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
RNA cap guanine-N2 methyltransferase RNA_cap_Gua-N2-MeTrfase IPR019012 ENSMUSP00000112121 Pfam 294
352 Description available Search pathways
tRNA transferase Trm5/Tyw2 tRNA_Trfase_Trm5/Tyw2 IPR003402 ENSMUSP00000112121 Pfam 192
412 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved