Arl4d - SNV Details



 Gene Information 
Gene Name Arl4d
Old Gene Names for Arl4d 1110036h21rik , Arf4l , Aw456149 , Arfl4
Gene Description ADP-ribosylation factor-like 4D [Source:MGI Symbol;Acc:MGI:1933155]
Uniprot Name
CCDS Name
Gene GO
cytoplasm; protein transport; intracellular; GTPase activity; small GTPase mediated signal transduction; protein binding; intracellular protein transport; nucleus; GTP binding; plasma membrane; biological_process; nucleolus; molecular_function
Homolog in other species ARL4D
Omim http://omim.org/entry/600732
Immgen Expression
MEDIAN(HIGH IN TGD GROUP, NK GROUP, T.8EFF.SP.OT1.D6.VSVOVA, T.4MEM.SP)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000034936
Chromosome 11
Coordinate 101,667,154     (Assembly: GRCm38)    
Ref Base A
Codon Change Agt/Ggt
Var Base G
Zygosity Heterozygous
Read Depth 11
Allele Frequency
A:R0.55
G:V0.46
Amino Acid Position 169
Amino Acid Change S->G (Serine -> Glycine)
Sample ID IGL02566
Median Base Quality 39
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 25 Other Mutations

 Predictions 
Polyphen Score 0.79
Polyphen Prediction Possibly damaging
Sift Score 0.01
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000035918:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Small GTPase superfamily Small_GTPase IPR001806 ENSMUSP00000035918 Pfam 24
186 Description available Search pathways
Elongation factor, GTP-binding domain EF_GTP-bd_dom IPR000795 ENSMUSP00000035918 Pfam 88
186 Description available Search pathways
Small GTPase superfamily, SAR1-type Small_GTPase_SAR1 IPR006687 ENSMUSP00000035918 Smart 5
187 Description available Search pathways
Small GTPase superfamily, Rab type Small_GTPase_Rab_type IPR003579 ENSMUSP00000035918 Smart 22
190 Description available Search pathways
Small GTPase superfamily, ARF type Small_GTPase_ARF IPR024156 ENSMUSP00000035918 Smart 1
191 Description available Search pathways
P-loop containing nucleoside triphosphate hydrolase P-loop_NTPase IPR027417 ENSMUSP00000035918 Superfamily 19
193 Description available Search pathways
Small GTPase superfamily, ARF/SAR type Small_GTPase_ARF/SAR IPR006689 ENSMUSP00000035918 Pfam 14
187 Description available Search pathways

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved