Ints1 - SNV Details

 Gene Information 
Gene Name Ints1
Old Gene Names for Ints1 1110015k06rik
Gene Description integrator complex subunit 1 [Source:MGI Symbol;Acc:MGI:1915760]
MGI phenotype Homozygous mutation of this gene results in embryonic lethality at the blastocyst stage.
Uniprot Name
Gene GO
blastocyst growth; inner cell mass cell proliferation; integral to membrane; negative regulation of apoptotic process; binding; nucleus; snRNA processing; U2 snRNA 3'-end processing; integrator complex; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; nuclear membrane; molecular_function
Homolog in other species INTS1
Immgen Expression
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000029547
Chromosome 5
Coordinate 139,771,637     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 15
Allele Frequency
Amino Acid Change V->E (Valine -> Glutamic acid)
Sample ID IGL02557
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 46 Other Mutations


 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved