Tanc1 - SNV Details



 Gene Information 
Gene Name Tanc1
Old Gene Names for Tanc1 1200003e16rik
Gene Description tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 [Source:MGI Symbol;Acc:MGI:1914110]
MGI phenotype Mice homozygous for a gene trap vector exhibit decreased spine density in the CA3 region and impaired spatial memory.
Uniprot Name
CCDS Name
Gene GO
postsynaptic membrane; axon terminus; visual learning; dendritic spine maintenance; protein binding; neuronal cell body; cell junction; myoblast fusion; plasma membrane; dendrite; postsynaptic density; molecular_function
Homolog in other species TANC1
Immgen Expression
MEDIAN(HIGH IN TGD GROUP, ABT GROUP, TACTIVATION GROUP)
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000035168
Chromosome 2
Coordinate 59,833,258     (Assembly: GRCm38)    
Ref Base G
Var Base T
Zygosity Heterozygous
Read Depth 33
Allele Frequency
G:R0.67
T:V0.33
Amino Acid Change G->C (Glycine -> Cysteine)
Sample ID IGL02540
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 29 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved