Tec - SNV Details



 Gene Information 
Gene Name Tec
Gene Description tec protein tyrosine kinase [Source:MGI Symbol;Acc:MGI:98662]
Uniprot Name
CCDS Name
Gene GO
intracellular signal transduction; protein kinase activity; regulation of platelet activation; cytoplasm; metal ion binding; intracellular; transferase activity
transferring phosphorus-containing groups; protein binding; non-membrane spanning protein tyrosine kinase activity; cytoskeleton; protein phosphorylation; protein tyrosine kinase activity; ATP binding; plasma membrane; integrin-mediated signaling pathway; B cell receptor signaling pathway; phospholipid binding
Homolog in other species TEC
Omim http://omim.org/entry/227050
Immgen Expression
MEDIAN(HIGH IN BCELL GROUP, DC GROUP, NK GROUP)
Gnf Expression
MEDIAN/HIGH(HIGH IN RETINA, PITUITARY, DORSALROOTGANGLION, TRIGEMINAL, KIDNEY, LIVER, IMM.G1, IMM.G3, OSTEO GROUP, C2C12, UMBLICALCORD, NIH.3T3, EPITH GROUP, TRACHEA, LUNG, BLADDER, UTERUS, OVARY, ADIPOSETISSUE, ADRENALGLAND)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000029217
Chromosome 5
Coordinate 72,779,415     (Assembly: GRCm38)    
Ref Base A
Var Base G
Zygosity Heterozygous
Read Depth 97
Allele Frequency
A:R0.55
G:V0.45
Amino Acid Change Disrupted splicing
Splice Position 6
Sample ID IGL02527
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 50 Other Mutations

 Predictions 
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved