Cux2 - SNV Details



 Gene Information 
Gene Name Cux2
Old Gene Names for Cux2 Cutl2 , Ensmusg00000072641 , 1700051k22rik
Gene Description cut-like homeobox 2 [Source:MGI Symbol;Acc:MGI:107321]
MGI phenotype Homozygotes for a targeted null mutation exhibit various neural defects.
Uniprot Name
CCDS Name
Gene GO
sequence-specific DNA binding; negative regulation of transcription
DNA-dependent; transcription
DNA-dependent; cellular response to organic substance; DNA binding; sequence-specific DNA binding transcription factor activity; nucleus; regulation of transcription
DNA-dependent
Homolog in other species CUX2
Immgen Expression
MEDIAN(LOWER IN DC8+.TH, TGD.VG5+.ACT.IEL)
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000042589
Chromosome 5
Coordinate 121,860,822     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 47
Allele Frequency
G:R0.45
A:V0.55
Amino Acid Change P->S (Proline -> Serine)
Sample ID IGL02508
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 62 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved