Bglap2 - SNV Details

 Gene Information 
Gene Name Bglap2
Gene Description bone gamma-carboxyglutamate protein 2 [Source:MGI Symbol;Acc:MGI:88157]
MGI phenotype Mice homozygous for a knock-out allele of both Bglap1 and Bglap2 exhibit decreased circulating insulin, impaired glucose tolerance, increased adipose tissue, increased bone density, and decreased male fertility.
Uniprot Name
Gene GO
type B pancreatic cell proliferation; pancreas development; biomineral tissue development; regulation of bone mineralization; positive regulation of insulin secretion; extracellular region; hydroxyapatite binding; cellular lipid catabolic process; calcium ion binding; glucose homeostasis; extracellular space; cellular response to insulin stimulus
Immgen Expression
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000074486
Chromosome 3
Coordinate 88,377,936     (Assembly: GRCm38)    
Ref Base A
Var Base T
Zygosity Heterozygous
Read Depth 18
Allele Frequency
Amino Acid Change C->Stop (Cysteine -> Stop)
Sample ID IGL02494
Median Base Quality 37.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 45 Other Mutations

Polyphen Prediction N/A

 Availability Details 
Availability Progeny Cryopreserved