Tpte - SNV Details



 Gene Information 
Gene Name Tpte
Gene Description transmembrane phosphatase with tensin homology [Source:MGI Symbol;Acc:MGI:2446460]
Uniprot Name
CCDS Name
Gene GO
protein dephosphorylation; integral to membrane; protein tyrosine/serine/threonine phosphatase activity; dephosphorylation; protein tyrosine phosphatase activity; protein binding; ion channel activity; biological_process; phosphatase activity; Golgi apparatus; molecular_function
Homolog in other species TPTE
Omim http://omim.org/entry/604336
Immgen Expression
LOW
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000031481
Chromosome 8
Coordinate 22,305,858     (Assembly: GRCm38)    
Ref Base T
Codon Change aTa/aAa
Var Base A
Zygosity Heterozygous
Read Depth 26
Allele Frequency
T:R0.65
A:V0.35
Amino Acid Position 79
Amino Acid Change I->K (Isoleucine -> Lysine)
Sample ID IGL02458
Median Base Quality 41
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 69 Other Mutations

 Predictions 
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Availability Details 
Availability Progeny Cryopreserved