Mtg1 - SNV Details



 Gene Information 
Gene Name Mtg1
Old Gene Names for Mtg1 Gm169 , Gtpbp7
Gene Description mitochondrial GTPase 1 homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2685015]
Uniprot Name
CCDS Name
Gene GO
mitochondrion; ribosome biogenesis; GTP catabolic process; integral to membrane; GTPase activity; ferrous iron transport; GTP binding; ferrous iron transmembrane transporter activity
Homolog in other species MTG1
Immgen Expression
MEDIAN(LOW IN GN.BM, HIGH IN B.GC.SP, PROB.FRBC.FL)
Gnf Expression
MEDIAN(HIGH IN M1)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000039018
Chromosome 7
Coordinate 140,150,172     (Assembly: GRCm38)    
Ref Base C
Codon Change Cag/Aag
Var Base A
Zygosity Heterozygous
Read Depth 39
Allele Frequency
C:R0.69
A:V0.31
Amino Acid Position 294
Amino Acid Change Q->K (Glutamine -> Lysine)
Sample ID IGL02458
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 69 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.32
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000036491:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
GTPase, MTG1 GTPase_MTG1 IPR016478 ENSMUSP00000036491 PIRSF 24
323 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved