Ypel1 - SNV Details



 Gene Information 
Gene Name Ypel1
Old Gene Names for Ypel1 0610009l05rik , C130078a06rik , Aa589416 , 1700019o22rik , Av118478 , Ppil2 , 4921520k19rik , 4930511f14rik
Gene Description peptidylprolyl isomerase (cyclophilin)-like 2 [Source:MGI Symbol;Acc:MGI:2447857]
Uniprot Name
CCDS Name
Gene GO
protein polyubiquitination; ubiquitin ligase complex; ubiquitin-protein ligase activity; protein ubiquitination; nucleus; protein folding; ubiquitin-ubiquitin ligase activity; peptidyl-prolyl cis-trans isomerase activity
Homolog in other species PPIL2
Omim http://omim.org/entry/607588
Immgen Expression
HIGH
Gnf Expression
HIGH
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000022771
Chromosome 16
Coordinate 17,088,838     (Assembly: GRCm38)    
Ref Base T
Codon Change Acc/Gcc
Var Base C
Zygosity Heterozygous
Read Depth 20
Allele Frequency
T:R0.70
C:V0.30
Amino Acid Position 500
Amino Acid Change T->A (Threonine -> Alanine)
Sample ID IGL02392
Median Base Quality 37.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 42 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.45
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved