Cdh8 - SNV Details



 Gene Information 
Gene Name Cdh8
Old Gene Names for Cdh8 Ai851472
Gene Description cadherin 8 [Source:MGI Symbol;Acc:MGI:107434]
Uniprot Name
CCDS Name
Gene GO
response to cold; synaptic transmission; axon terminus; synaptic transmission
glutamatergic; membrane; integral to membrane; homophilic cell adhesion; synaptic cleft; plasma membrane; calcium ion binding
Homolog in other species CDH8
Omim http://omim.org/entry/603008
Immgen Expression
LOW
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000036510
Chromosome 8
Coordinate 99,030,755     (Assembly: GRCm38)    
Ref Base G
Codon Change aCg/aTg
Var Base A
Zygosity Heterozygous
Read Depth 41
Allele Frequency
G:R0.54
A:V0.46
Amino Acid Position 737
Amino Acid Change T->M (Threonine -> Methionine)
Sample ID IGL02392
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 42 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0.04
Sift Prediction deleterious

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved