Brat1 - SNV Details



 Gene Information 
Gene Name Brat1
Old Gene Names for Brat1 Baat1 , Aa881470
Gene Description BRCA1-associated ATM activator 1 [Source:MGI Symbol;Acc:MGI:1891679]
Uniprot Name
CCDS Name
Gene GO
response to ionizing radiation; protein binding; binding; nucleus
Homolog in other species BRAT1
Omim http://omim.org/entry/614506
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000000148
Chromosome 5
Coordinate 140,712,808     (Assembly: GRCm38)    
Ref Base C
Codon Change gCc/gTc
Var Base T
Zygosity Heterozygous
Read Depth 35
Allele Frequency
C:R0.43
T:V0.57
Amino Acid Position 245
Amino Acid Change A->V (Alanine -> Valine)
Sample ID IGL02437
Median Base Quality 35
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 59 Other Mutations

 Predictions 
Polyphen Score 0.93
Polyphen Prediction Possibly damaging
Sift Score 0.2
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000036016:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Armadillo-type fold ARM-type_fold IPR016024 ENSMUSP00000036016 Superfamily 4
661 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved