Casc4 - SNV Details



 Gene Information 
Gene Name Casc4
Old Gene Names for Casc4 D130060c09rik
Gene Description cancer susceptibility candidate 4 [Source:MGI Symbol;Acc:MGI:2443129]
Uniprot Name
CCDS Name
Gene GO
integral to membrane; cellular_component; biological_process; molecular_function
Homolog in other species CASC4
Immgen Expression
MEDIAN(HIGH IN BCELL GROUP, TGD GROUP, ABT GROUP, TACTIVATION GROUP, NK GROUP, DC.PDC.8-.SP, DC.PDC.8+.SP)
Gnf Expression
MEDIAN
MEDIAN(HIGH IN NS GROUP, IMM.G1, IMM.G3, OSTEO GROUP, EPITH GROUP, EMB GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000060227
Chromosome 2
Coordinate 121,911,987     (Assembly: GRCm38)    
Ref Base A
Codon Change Acg/Gcg
Var Base G
Zygosity Heterozygous
Read Depth 34
Allele Frequency
A:R0.62
G:V0.38
Amino Acid Position 339
Amino Acid Change T->A (Threonine -> Alanine)
Sample ID IGL02429
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 56 Other Mutations

 Predictions 
Polyphen Score 0.66
Polyphen Prediction Possibly damaging
Sift Score 0.53
Sift Prediction tolerated

 Availability Details 
Availability Progeny Cryopreserved