Cul9 - SNV Details



 Gene Information 
Gene Name Cul9
Old Gene Names for Cul9 1810035i07rik , Parc
Gene Description cullin 9 [Source:MGI Symbol;Acc:MGI:1925559]
MGI phenotype Mice homozygous for a knock-out allele exhibit decreased body weight, increased incidence of tumors, and decreased cellular sensitivity to radiation-induced apoptosis.
Uniprot Name
CCDS Name
Gene GO
ubiquitin protein ligase binding; zinc ion binding; ubiquitin-dependent protein catabolic process; protein binding; binding; cullin-RING ubiquitin ligase complex
Homolog in other species CUL9
Omim http://omim.org/entry/607489
Immgen Expression
MEDIAN(HIGH IN DC.PDC.8-.SP, DC.PDC.8+.SP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000040327
Chromosome 17
Coordinate 46,523,258     (Assembly: GRCm38)    
Ref Base T
Codon Change Acg/Ccg
Var Base G
Zygosity Heterozygous
Read Depth 54
Allele Frequency
T:R0.44
G:V0.56
Amino Acid Position 1253
Amino Acid Change T->P (Threonine -> Proline)
Sample ID IGL02426
Median Base Quality 35
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 36 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious

 Availability Details 
Availability Progeny Cryopreserved