Arhgef16 - SNV Details



 Gene Information 
Gene Name Arhgef16
Gene Description Rho guanine nucleotide exchange factor (GEF) 16 [Source:MGI Symbol;Acc:MGI:2446219]
Uniprot Name
CCDS Name
Gene GO
activation of Rac GTPase activity; cytoplasm; intracellular; Rho guanyl-nucleotide exchange factor activity; protein binding; positive regulation of establishment of protein localization to plasma membrane; PDZ domain binding; receptor tyrosine kinase binding; cell chemotaxis; activation of Cdc42 GTPase activity; Rho GTPase binding; regulation of Rho protein signal transduction; phospholipid binding
Homolog in other species ARHGEF16
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
LOW
MEDIAN(HIGH IN M1, BLASTOCYSTS, GI GROUP, EPITH GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000029032
Chromosome 4
Coordinate 154,287,065     (Assembly: GRCm38)    
Ref Base G
Var Base A
Zygosity Heterozygous
Read Depth 10
Allele Frequency
G:R0.70
A:V0.30
Amino Acid Change R->Stop (Arginine -> Stop)
Sample ID IGL02422
Median Base Quality 37.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 46 Other Mutations

 Predictions 
Polyphen Prediction N/A

 Availability Details 
Availability Progeny Cryopreserved