Llgl2 - SNV Details



 Gene Information 
Gene Name Llgl2
Gene Description lethal giant larvae homolog 2 (Drosophila) [Source:MGI Symbol;Acc:MGI:1918843]
Uniprot Name
CCDS Name
Gene GO
regulation of establishment or maintenance of cell polarity; cell division; cytoplasm; cell cycle; intracellular membrane-bounded organelle; protein binding; PDZ domain binding; integrin-mediated signaling pathway; exocytosis
Homolog in other species LLGL2
Immgen Expression
MEDIAN(HIGH IN TGD GROUP, ABT GROUP, TACTIVATION GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000020782
Chromosome 11
Coordinate 115,853,285     (Assembly: GRCm38)    
Ref Base A
Codon Change Atg/Gtg
Var Base G
Zygosity Heterozygous
Read Depth 30
Allele Frequency
A:R0.60
G:V0.40
Amino Acid Position 773
Amino Acid Change M->V (Methionine -> Valine)
Sample ID IGL02415
Median Base Quality 37.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 52 Other Mutations

 Predictions 
Sift Score 0.05
Sift Prediction tolerated

 Availability Details 
Availability Progeny Cryopreserved