Stk32a - SNV Details



 Gene Information 
Gene Name Stk32a
Old Gene Names for Stk32a A930015b13rik
Gene Description serine/threonine kinase 32A [Source:MGI Symbol;Acc:MGI:2442403]
Uniprot Name
CCDS Name
Gene GO
protein kinase activity; metal ion binding; transferase activity
transferring phosphorus-containing groups; cellular_component; protein phosphorylation; protein tyrosine kinase activity; ATP binding; protein serine/threonine kinase activity
Homolog in other species STK32A
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000039954
Chromosome 18
Coordinate 43,297,511     (Assembly: GRCm38)    
Ref Base T
Codon Change aTc/aCc
Var Base C
Zygosity Heterozygous
Read Depth 50
Allele Frequency
T:R0.64
C:V0.36
Amino Acid Position 162
Amino Acid Change I->T (Isoleucine -> Threonine)
Sample ID IGL02407
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 61 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Protein domains 
ENSMUSP00000038471:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Serine/threonine- / dual specificity protein kinase, catalytic domain Ser/Thr_dual-sp_kinase_dom IPR002290 ENSMUSP00000038471 Smart 23
281 Description available Search pathways
Tyrosine-protein kinase, catalytic domain Tyr_kinase_cat_dom IPR020635 ENSMUSP00000038471 Smart 23
278 Description available Search pathways
Protein kinase-like domain Kinase-like_dom IPR011009 ENSMUSP00000038471 Superfamily 9
312 Description available Search pathways
Serine-threonine/tyrosine-protein kinase catalytic domain Ser-Thr/Tyr_kinase_cat_dom IPR001245 ENSMUSP00000038471 Pfam 24
270 Description available Search pathways
Protein kinase domain Prot_kinase_cat_dom IPR000719 ENSMUSP00000038471 Pfam 23
280 Description available Search pathways
Protein kinase domain Prot_kinase_cat_dom IPR000719 ENSMUSP00000038471 Prosite_profiles 23
281 Description available Search pathways

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved