Dhrs7 - SNV Details



 Gene Information 
Gene Name Dhrs7
Old Gene Names for Dhrs7 2310016e22rik , 5730564l20rik , Aw061210
Gene Description dehydrogenase/reductase (SDR family) member 7 [Source:MGI Symbol;Acc:MGI:1913625]
Uniprot Name
CCDS Name
Gene GO
oxidoreductase activity; metabolic process; cellular_component; nucleotide binding; biological_process
Homolog in other species DHRS7
Omim http://omim.org/entry/612833
Immgen Expression
MEDIAN(HIGH IN GN.BM)
Gnf Expression
MEDIAN
MEDIAN(HIGH IN KIDNEY, LIVER, IMM GROUP, OSTEO GROUP, PROSTATE)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000021094
Chromosome 12
Coordinate 72,664,692     (Assembly: GRCm38)    
Ref Base G
Codon Change Cgc/Tgc
Var Base A
Zygosity Heterozygous
Read Depth 30
Allele Frequency
G:R0.50
A:V0.50
Amino Acid Position 24
Amino Acid Change R->C (Arginine -> Cysteine)
Sample ID IGL02398
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 52 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0.15
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Progeny Cryopreserved