Cyp3a59 - SNV Details



 Gene Information 
Gene Name Cyp3a59
Old Gene Names for Cyp3a59 Ensmusg00000061292
Gene Description cytochrome P450, subfamily 3A, polypeptide 59 [Source:MGI Symbol;Acc:MGI:3769707]
Uniprot Name
CCDS Name
Gene GO
oxidation-reduction process; oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen
reduced flavin or flavoprotein as one donor
and incorporation of one atom of oxygen; heme binding; cellular_component; oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen; biological_process; electron carrier activity; iron ion binding; molecular_function
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000061292
Chromosome 5
Coordinate 146,079,342     (Assembly: GRCm38)    
Ref Base T
Codon Change cTc/cCc
Var Base C
Zygosity Heterozygous
Read Depth 216
Allele Frequency
T:R0.50
C:V0.50
Amino Acid Position 3
Amino Acid Change L->P (Leucine -> Proline)
Sample ID IGL02350
Median Base Quality 35
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 50 Other Mutations

 Predictions 
Polyphen Score 0.77
Polyphen Prediction Possibly damaging
Sift Score 0.01
Sift Prediction deleterious

 Availability Details 
Availability Cryopreserved