Cyp2d12 - SNV Details



 Gene Information 
Gene Name Cyp2d12
Old Gene Names for Cyp2d12 9030605e09rik
Gene Description cytochrome P450, family 2, subfamily d, polypeptide 12 [Source:MGI Symbol;Acc:MGI:88604]
Uniprot Name
CCDS Name
Gene GO
oxidation-reduction process; oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen
reduced flavin or flavoprotein as one donor
and incorporation of one atom of oxygen; heme binding; cellular_component; oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen; biological_process; electron carrier activity; iron ion binding; molecular_function
Immgen Expression
LOW
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000096852
Chromosome 15
Coordinate 82,558,970     (Assembly: GRCm38)    
Ref Base T
Codon Change gTc/gCc
Var Base C
Zygosity Heterozygous
Read Depth 91
Allele Frequency
T:R0.64
C:V0.36
Amino Acid Position 411
Amino Acid Change V->A (Valine -> Alanine)
Sample ID IGL02353
Median Base Quality 35
Backgrounds C57BL/6j
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 30 Other Mutations

 Predictions 
Polyphen Score 0.17
Polyphen Prediction Benign
Sift Score 0.17
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000071064:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Cytochrome P450 Cyt_P450 IPR001128 ENSMUSP00000071064 Pfam 37
496 Description available Search pathways
Cytochrome P450 Cyt_P450 IPR001128 ENSMUSP00000071064 Superfamily 34
501 Description available Search pathways

 Availability Details 
Availability Cryopreserved