Cyp2d11 - SNV Details



 Gene Information 
Gene Name Cyp2d11
Gene Description cytochrome P450, family 2, subfamily d, polypeptide 11 [Source:MGI Symbol;Acc:MGI:88603]
Uniprot Name
CCDS Name
Gene GO
oxidation-reduction process; oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen
reduced flavin or flavoprotein as one donor
and incorporation of one atom of oxygen; heme binding; cellular_component; oxidoreductase activity
acting on paired donors
with incorporation or reduction of molecular oxygen; biological_process; electron carrier activity; iron ion binding; molecular_function
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000068085
Chromosome 15
Coordinate 82,390,480     (Assembly: GRCm38)    
Ref Base G
Codon Change Cgc/Tgc
Var Base A
Zygosity Heterozygous
Read Depth 65
Allele Frequency
G:R0.55
A:V0.45
Amino Acid Position 299
Amino Acid Change R->C (Arginine -> Cysteine)
Sample ID IGL02347
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 50 Other Mutations

 Predictions 
Polyphen Score 0.03
Polyphen Prediction Benign
Sift Score 0.19
Sift Prediction tolerated

 Availability Details 
Availability Cryopreserved