Fibcd1 - SNV Details



 Gene Information 
Gene Name Fibcd1
Old Gene Names for Fibcd1 Ai448887
Gene Description fibrinogen C domain containing 1 [Source:MGI Symbol;Acc:MGI:2138953]
Uniprot Name
CCDS Name
Gene GO
membrane; integral to membrane; signal transduction; metal ion binding; chitin binding; receptor binding; extracellular space
Homolog in other species FIBCD1
Omim http://omim.org/entry/613357
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
MEDIAN
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000026841
Chromosome 2
Coordinate 31,816,592     (Assembly: GRCm38)    
Ref Base T
Codon Change tAc/tGc
Var Base C
Zygosity Heterozygous
Read Depth 21
Allele Frequency
T:R0.67
C:V0.33
Amino Acid Position 409
Amino Acid Change Y->C (Tyrosine -> Cysteine)
Sample ID IGL02345
Median Base Quality 34
Backgrounds C57BL/6j
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 33 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Protein domains 
ENSMUSP00000028188:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen_a/b/g_C_dom IPR002181 ENSMUSP00000028188 Superfamily 238
457 Description available Search pathways
Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen_a/b/g_C_dom IPR002181 ENSMUSP00000028188 Smart 237
455 Description available Search pathways
Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen_a/b/g_C_dom IPR002181 ENSMUSP00000028188 Pfam 239
455 Description available Search pathways

 Availability Details 
Availability Cryopreserved