Neo1 - SNV Details



 Gene Information 
Gene Name Neo1
Old Gene Names for Neo1 2610028h22rik , Ai327052 , D930014n22rik
Gene Description neogenin [Source:MGI Symbol;Acc:MGI:1097159]
MGI phenotype Mice homozygous for a gene trap allele display perinatal lethality and abnormal trigeminal nerve development.
Uniprot Name
CCDS Name
Gene GO
iron ion homeostasis; cadherin binding; integral to membrane; receptor activity; protein binding; myoblast fusion; regulation of transcription
DNA-dependent
Homolog in other species NEO1
Omim http://omim.org/entry/601907
Immgen Expression
LOW(HIGH IN DC.LC.SK)
Gnf Expression
MEDIAN
HIGH(LOWER IN FERTILIZED EGG, OOCYTE, PANCREAS, SPLEEN, BONE MARROW, THYROID)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000032340
Chromosome 9
Coordinate 58,903,088     (Assembly: GRCm38)    
Ref Base T
Codon Change Acg/Gcg
Var Base C
Zygosity Heterozygous
Read Depth 19
Allele Frequency
T:R0.42
C:V0.58
Amino Acid Position 1027
Amino Acid Change T->A (Threonine -> Alanine)
Sample ID IGL02327
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 41 Other Mutations

 Predictions 
Polyphen Score 0.1
Polyphen Prediction Benign
Sift Score 0.24
Sift Prediction tolerated

 Availability Details 
Availability Cryopreserved