Kcnn3 - SNV Details



 Gene Information 
Gene Name Kcnn3
Gene Description potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:MGI Symbol;Acc:MGI:2153183]
Uniprot Name
CCDS Name
Gene GO
integral to membrane; cytoplasm; calcium-activated potassium channel activity; calmodulin binding; small conductance calcium-activated potassium channel activity; plasma membrane; potassium ion transport
Homolog in other species KCNN3
Omim http://omim.org/entry/602983
Immgen Expression
MEDIAN(HIGH IN TGD.VG5+.ACT.IEL, NK GROUP, T.8EFF.SP.OT1.D6.VSVOVA, DC.LC.SK, MYELOID GROUP)
Gnf Expression
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000000794
Chromosome 3
Coordinate 89,661,218     (Assembly: GRCm38)    
Ref Base A
Codon Change cAc/cGc
Var Base G
Zygosity Heterozygous
Read Depth 16
Allele Frequency
A:R0.62
G:V0.38
Amino Acid Position 601
Amino Acid Change H->R (Histidine -> Arginine)
Sample ID IGL02263
Median Base Quality 39.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 26 Other Mutations

 Predictions 
Polyphen Score 0.98
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved