Itga11 - SNV Details



 Gene Information 
Gene Name Itga11
Old Gene Names for Itga11 4732459h24rik
Gene Description integrin alpha 11 [Source:MGI Symbol;Acc:MGI:2442114]
MGI phenotype Mice homozygous for a disruption of this gene display dwarfism, increased mortality with age, and defective incisors.
Uniprot Name
CCDS Name
Gene GO
protein binding
Homolog in other species ITGA11
Omim http://omim.org/entry/604789
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
MEDIAN(HIGH IN RETINA, PITUITARY, DORSALROOTGANGLION, TRIGEMINAL, KIDNEY, LIVER, C2C12, UMBLICALCORD, NIH.3T3, OSTEOBLASTS, EPITH GROUP, IMM.G2, TRACHEA, PROSTATE, LUNG, BLADDER, UTERUS, OVARY, ADIPOSETISSUE, ADRENALGLAND)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000032243
Chromosome 9
Coordinate 62,755,775     (Assembly: GRCm38)    
Ref Base T
Var Base C
Zygosity Heterozygous
Read Depth 45
Allele Frequency
T:R0.38
C:V0.62
Amino Acid Change Disrupted splicing
Splice Position 2
Sample ID IGL02237
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 54 Other Mutations

 Predictions 
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved