Ptpn21 - SNV Details



 Gene Information 
Gene Name Ptpn21
Gene Description protein tyrosine phosphatase, non-receptor type 21 [Source:MGI Symbol;Acc:MGI:1344406]
Uniprot Name
CCDS Name
Gene GO
protein dephosphorylation; dephosphorylation; protein tyrosine phosphatase activity; cytoskeleton; phosphatase activity
Homolog in other species PTPN21
Omim http://omim.org/entry/603271
Immgen Expression
MEDIAN(LOW IN GN.BM)
Gnf Expression
MEDIAN(HIGH IN FERTILIZEDEGG, OOCYTE, KIDNEY, LIVER, C2C12, UMBLICALCORD, NIH.3T3, OSTEOBLASTS, EMB GROUP, EPITH GROUP, SALIVARYGLAND, THYROID, PLACENTA, GI GROUP, TRACHEA, PROSTATE, LUNG, BLADDER, UTERUS, OVARY)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000021009
Chromosome 12
Coordinate 98,705,092     (Assembly: GRCm38)    
Ref Base C
Var Base T
Zygosity Heterozygous
Read Depth 111
Allele Frequency
C:R0.51
T:V0.49
Amino Acid Change Disrupted splicing
Splice Position 1
Sample ID IGL02237
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 54 Other Mutations

 Predictions 
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved