Rps6kc1 - SNV Details



 Gene Information 
Gene Name Rps6kc1
Old Gene Names for Rps6kc1 Aa960234 , Rps6kc1 , B130003f20rik , C80612 , Aa682037
Gene Description ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:2443419]
Uniprot Name
CCDS Name
Gene GO
protein kinase activity; early endosome; membrane; cytoplasm; cell communication; transferase activity
transferring phosphorus-containing groups; protein binding; phosphatidylinositol binding; protein phosphorylation; ATP binding; biological_process; protein serine/threonine kinase activity; molecular_function
Homolog in other species RPS6KC1
Immgen Expression
MEDIAN/HIGH(HIGH IN BCELL GROUP, MYELOID GROUP, DC GROUP)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000089872
Chromosome 1
Coordinate 190,871,836     (Assembly: GRCm38)    
Ref Base A
Codon Change agT/agA
Var Base T
Zygosity Heterozygous
Read Depth 31
Allele Frequency
A:R0.39
T:V0.61
Amino Acid Position 196
Amino Acid Change S->R (Serine -> Arginine)
Sample ID IGL02178
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 54 Other Mutations

 Predictions 
Polyphen Score 0.09
Polyphen Prediction Benign
Sift Score 0.36
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability