Rps6kc1 - SNV Details



 Gene Information 
Gene Name Rps6kc1
Old Gene Names for Rps6kc1 Aa960234 , Rps6kc1 , B130003f20rik , C80612 , Aa682037
Gene Description ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:2443419]
Uniprot Name
CCDS Name
Gene GO
protein kinase activity; early endosome; membrane; cytoplasm; cell communication; transferase activity
transferring phosphorus-containing groups; protein binding; phosphatidylinositol binding; protein phosphorylation; ATP binding; biological_process; protein serine/threonine kinase activity; molecular_function
Homolog in other species RPS6KC1
Immgen Expression
MEDIAN/HIGH(HIGH IN BCELL GROUP, MYELOID GROUP, DC GROUP)
Gnf Expression
MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000089872
Chromosome 1
Coordinate 190,871,836     (Assembly: GRCm38)    
Ref Base A
Codon Change agT/agA
Var Base T
Zygosity Heterozygous
Read Depth 31
Allele Frequency
A:R0.39
T:V0.61
Amino Acid Position 196
Amino Acid Change S->R (Serine -> Arginine)
Sample ID IGL02178
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 54 Other Mutations

 Predictions 
Polyphen Score 0.09
Polyphen Prediction Benign
Sift Score 0.36
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Progeny Cryopreserved