Las1l - SNV Details



 Gene Information 
Gene Name Las1l
Old Gene Names for Las1l 1810030a06rik , 5830482g23rik
Gene Description LAS1-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1923380]
Uniprot Name
CCDS Name
Gene GO
MLL1 complex; cytoplasm; nucleus; rRNA processing; biological_process; nucleolus; molecular_function
Homolog in other species LAS1L
Immgen Expression
MEDIAN(LOW IN GN.BM, HIGH IN B.GC.SP, PROB.FRBC.FL)
Gnf Expression
MEDIAN(HIGH IN TESTIS, FERTILIZEDEGG, OOCYTE, IMM.G1, IMM.G3, OSTEO GROUP, M1, EMBRYONIC.STEM TISSUES)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000057421
Chromosome X
Coordinate 95,953,302     (Assembly: GRCm38)    
Ref Base A
Codon Change gTg/gCg
Var Base G
Zygosity Heterozygous
Read Depth 55
Allele Frequency
A:R0.65
G:V0.34
Amino Acid Position 130
Amino Acid Change V->A (Valine -> Alanine)
Sample ID IGL02152
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 63 Other Mutations

 Predictions 
Polyphen Score 0.96
Polyphen Prediction Probably damaging

 Availability Details 
Availability Progeny Cryopreserved