Aldh16a1 - SNV Details



 Gene Information 
Gene Name Aldh16a1
Old Gene Names for Aldh16a1 2410004h02rik , Ai452234
Gene Description aldehyde dehydrogenase 16 family, member A1 [Source:MGI Symbol;Acc:MGI:1916998]
Uniprot Name
CCDS Name
Gene GO
oxidation-reduction process; oxidoreductase activity; oxidoreductase activity
acting on the aldehyde or oxo group of donors
NAD or NADP as acceptor; metabolic process; cellular_component
Homolog in other species ALDH16A1
Omim http://omim.org/entry/613358
Immgen Expression
MEDIAN(HIGH IN DC.PDC.8-.SP, DC.PDC.8+.SP)
Gnf Expression
MEDIAN(HIGH IN IMM.G1, IMM.G3)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000007833
Chromosome 7
Coordinate 45,146,035     (Assembly: GRCm38)    
Ref Base G
Codon Change cCg/cTg
Var Base A
Zygosity Heterozygous
Read Depth 22
Allele Frequency
G:R0.45
A:V0.55
Amino Acid Position 400
Amino Acid Change P->L (Proline -> Leucine)
Sample ID IGL02126
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 52 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0.34
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved