Creb5 - SNV Details



 Gene Information 
Gene Name Creb5
Old Gene Names for Creb5 D430026c09rik
Gene Description cAMP responsive element binding protein 5 [Source:MGI Symbol;Acc:MGI:2443973]
MGI phenotype Mice homozygous for a null mutation display neonatal lethality.
Uniprot Name
CCDS Name
Gene GO
sequence-specific DNA binding; positive regulation of transcription from RNA polymerase II promoter; sequence-specific DNA binding transcription factor activity; adipose tissue development; protein binding; fat cell differentiation; nucleus; positive regulation of transcription
DNA-dependent; protein dimerization activity; regulation of transcription
DNA-dependent; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
Homolog in other species CREB5
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Gnf Expression
MEDIAN(HIGH IN BROWNFAT, HEART, IMM.G2)
MEDIAN(HIGH IN MACROPHAGES, OSTEOCLASTS)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000053007
Chromosome 6
Coordinate 53,604,458     (Assembly: GRCm38)    
Ref Base C
Var Base T
Zygosity Heterozygous
Read Depth 28
Allele Frequency
C:R0.43
T:V0.57
Amino Acid Change Disrupted splicing
Splice Position 4
Sample ID IGL02114
Median Base Quality 39.5
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 41 Other Mutations

 Predictions 

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved