Adck1 - SNV Details



 Gene Information 
Gene Name Adck1
Old Gene Names for Adck1 2610005a10rik
Gene Description aarF domain containing kinase 1 [Source:MGI Symbol;Acc:MGI:1919363]
Uniprot Name
CCDS Name
Gene GO
mitochondrion; protein kinase activity; transferase activity
transferring phosphorus-containing groups; protein phosphorylation; extracellular region; ATP binding; biological_process; protein serine/threonine kinase activity; molecular_function
Homolog in other species ADCK1
Immgen Expression
MEDIAN(HIGH IN DC.PDC.8-.SP, DC.PDC.8+.SP)
Gnf Expression
HIGH
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000021044
Chromosome 12
Coordinate 88,446,710     (Assembly: GRCm38)    
Ref Base G
Codon Change Gtc/Ttc
Var Base T
Zygosity Heterozygous
Read Depth 31
Allele Frequency
G:R0.68
T:V0.32
Amino Acid Position 271
Amino Acid Change V->F (Valine -> Phenylalanine)
Sample ID IGL02089
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 53 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Protein domains 
ENSMUSP00000098724:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Protein kinase-like domain Kinase-like_dom IPR011009 ENSMUSP00000098724 Superfamily 127
381 Description available Search pathways
Protein kinase domain Prot_kinase_cat_dom IPR000719 ENSMUSP00000098724 Pfam 154
337 Description available Search pathways
Protein kinase domain Prot_kinase_cat_dom IPR000719 ENSMUSP00000098724 Prosite_profiles 148
477 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved