Ccnl2 - SNV Details



 Gene Information 
Gene Name Ccnl2
Old Gene Names for Ccnl2 2010319m22rik , 1700010a01rik
Gene Description cyclin L2 [Source:MGI Symbol;Acc:MGI:1927119]
Uniprot Name
CCDS Name
Gene GO
transcription
DNA-dependent; regulation of cyclin-dependent protein kinase activity; protein binding; nuclear speck; nucleus; regulation of transcription
DNA-dependent; biological_process; protein kinase binding; RNA processing
Homolog in other species CCNL2
Omim http://omim.org/entry/613482
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
HIGH
Gnf Expression
LOW
HIGH
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000029068
Chromosome 4
Coordinate 155,821,862     (Assembly: GRCm38)    
Ref Base A
Codon Change Agc/Ggc
Var Base G
Zygosity Heterozygous
Read Depth 19
Allele Frequency
A:R0.53
G:V0.47
Amino Acid Position 351
Amino Acid Change S->G (Serine -> Glycine)
Sample ID IGL02029
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 33 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.43
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000030944:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Cyclin L Cyclin_L IPR017060 ENSMUSP00000030944 PIRSF 1
518 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved , Cryopreserved