Serpinb7 - SNV Details



 Gene Information 
Gene Name Serpinb7
Old Gene Names for Serpinb7 4631416m05rik
Gene Description serine (or cysteine) peptidase inhibitor, clade B, member 7 [Source:MGI Symbol;Acc:MGI:2151053]
Uniprot Name
CCDS Name
Gene GO
cytoplasm; serine-type endopeptidase inhibitor activity; cellular_component; regulation of proteolysis; negative regulation of endopeptidase activity
Homolog in other species SERPINB7
Omim http://omim.org/entry/603357
Immgen Expression
LOW(HIGH IN DC.LC.SK)
Gnf Expression
LOW(HIGH IN RETINA, UMBLICALCORD. EPIDERMIS TISSUES, TRACHEA)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000067001
Chromosome 1
Coordinate 107,448,129     (Assembly: GRCm38)    
Ref Base G
Codon Change gGc/gTc
Var Base T
Zygosity Heterozygous
Read Depth 47
Allele Frequency
G:R0.49
T:V0.51
Amino Acid Position 159
Amino Acid Change G->V (Glycine -> Valine)
Sample ID IGL02008
Median Base Quality 39
Backgrounds Balb/c:C57BL/6
Source Walter and Eliza Hall Institute (WEHI-G1)
Other variants in this mouse 73 Other Mutations

 Predictions 
Polyphen Score 0.21
Polyphen Prediction Benign
Sift Score 0.03
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved