Dnah11 - SNV Details



 Gene Information 
Gene Name Dnah11
Old Gene Names for Dnah11 Dnahc11
Gene Description dynein, axonemal, heavy chain 11 [Source:MGI Symbol;Acc:MGI:1100864]
MGI phenotype Approximately half of live-born homozygous mutants show situs inversus indicating that this gene is no longer properly controlling left-right asymmetry.
Uniprot Name
CCDS Name
Gene GO
ATP binding
ATPase activity
axonemal dynein complex
ciliary or flagellar motility
cilium
determination of left/right symmetry
dynein complex
microtubule motor activity
microtubule-based movement
nucleoside-triphosphatase activity
nucleotide binding
Homolog in other species DNAH11
Omim http://omim.org/entry/603339
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.DPSM.TH, T.8EFF.SP.OT1.D6.VSVOVA, T.8MEM.LN,TGD.SP,T.4FP3+25+.SP,T.4NVE.PP)
Gnf Expression
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000018581
Chromosome 12
Coordinate 117,922,004     (Assembly: GRCm38)    
Ref Base T
Var Base A
Zygosity Heterozygous
Read Depth 38
Allele Frequency
T:0.66
A:0.34
Amino Acid Change Disrupted splicing
Sample ID IGL00687
Median Base Quality 39
Backgrounds C57BL/6n
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 11 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction N/A

 Availability Details 
Availability Progeny Cryopreserved